Work

Optimization of Mn-Zn ferrite doping in phosphate-based glass ceramics for enhanced hyperthermia efficiency and bioactivity

Year: 2024

Type: article

Abstract: This study investigates the effects of Mn-Zn ferrite (MZF) content and heat treatment temperature on the structural, mechanical, magnetic, and bioactive properties of Na 2 O-CaO-P 2 O 5 glass ceramics . Various MZF contents (5MZF, 10MZF, 20MZF, and 40MZF) were incorporated into the glass ceramics and subjected to heat treatment at different temperatures (600, 650, 700, and 800 °C). The results demonstrated that increasing the MZF content significantly enhanced the mechanical properties, including Vickers hardness , Knoop hardness, and Young's modulus . For example, the Vickers hardness values increased from 5.6 GPa in 5MZF samples to 7.1 GPa in 40MZF samples. X-ray diffraction analysis revealed the presence of major crystalline phases, such as Ca 2 P 2 O 7 and Na 4 Ca(PO 3 ) 6 , with NaFe 3 P 3 O 12 and (Zn,Mn)Fe 2 O 4 appearing in samples with higher MZF content. Magnetic measurements indicated that the 40MZF samples treated at 700 °C reached a satisfactory hyperthermia temperature of 43 °C within 16 min. Bioactivity tests showed a decrease in bioactivity with increasing MZF content, whereas cytotoxicity assays confirmed that all MZF-Na 2 O-CaO-P 2 O 5 bioactive glass ceramics were non-toxic, maintaining over 100 % cell viability after 24 h. These findings suggest that MZF-containing glass ceramics have potential applications in the biomedical field, particularly when enhanced mechanical and magnetic properties are required.

Source: Ceramics International

DOI: 10.1016/j.ceramint.2024.10.146