Possibilities of Predicting the Outcome of the Course of Acute Purulent-destructive Lung Diseases in Patients Who Have Had Sars-cov-2
Year: 2024
Type: article
Abstract: Since the discovery of COVID-19, purulent-destructive lung diseases have been increasingly described and diagnosed around the world in patients who have fallen ill with or have had covid pneumonia. Treatment of purulent diseases of the lungs and pleura invariably remains an urgent problem. This pathology, painful for the patient, time-consuming for the doctor and expensive for the medical institution, combines intoxication due to a purulent-destructive process and impaired respiratory function. The occurrence of infectious destruction of the lungs and pleura is facilitated by immunodeficiency and immunosuppression, which are characteristic of patients suffering from haematological diseases, increased tendency to thrombosis, diabetes mellitus, alcoholism, drug addiction, HIV infection, who have undergone extensive surgical interventions, organ and tissue transplantation. The peculiarity of the course of COVID lung infection is the consolidation of an inflammatory focus in the lungs, which can lead to the formation of abscesses and gangrene of the lungs, and sepsis, which is associated with high mortality in the long term after COVID disease. At the moment, the exact mechanism of development is not known, but it may be associated with diffuse alveolar damage, intraalveolar bleeding, stenosis or occlusion of alveolar arterioles, their thrombosis and, as a consequence of the above, necrosis of the cell parenchyma. Another factor in the occurrence of acute purulent-destructive lung diseases is pneumofibrosis, which is a frequent occurrence after covid pneumonia. A lung abscess is a necrotic lesion that forms a cavity filled with pus in the lung parenchyma with a characteristic level of fluid in the air on a chest X-ray. Most often, the cause of severe covid pneumonia is not only a virus but bacterial and fungal superinfection, including those associated with mechanical ventilation.
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4403311170