Work

Design, synthesis and mechanistic insights into triclosan derived dimers as potential anti-plasmodials

Year: 2024

Type: article

Abstract: CRT compared to TCS. To the best of our knowledge, this is the first report of triclosan-based compounds demonstrating promising heme-inhibition behaviour, with binding values comparable to those of chloroquine (CQ).

Source: RSC Medicinal Chemistry

DOI: 10.1039/d4md00494a

Authors: Shekhar, Shefali Chowdhary, Joel Mosnier, Isabelle Fonta, Bruno Pradines, Vipan Kumar

Institutions: Guru Nanak Dev University, Aix-Marseille Université, Méditerranée Infection Foundation, Risques Infectieux Tropicaux Microorganismes EmergentS

Language: English

Topic: Malaria Research and Control

Subfield: Public Health, Environmental and Occupational Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Council of Scientific and Industrial Research, India, University Grants Commission, Direction Générale de l’Armement, Northwest Fisheries Science Center

Awards: G2618568287, G4686379830, G583124245

OpenAlex ID: W4403317612

FWCI: 0.384

Cites: 47

Cited by: 1

Related to: 10