Work

Successful Use of Fecal Microbiota Transplantation in Management of Nonobstructive Recurrent Cholangitis Following Total Pancreatectomy and Islet Autotransplant

Year: 2024

Type: article

Abstract: ABSTRACT Alterations in the gut microbiome have been implicated in various pathologies. Fecal microbiota transplantation (FMT) has been offered as a novel treatment for conditions implicated in the disruption of the gut-microbiota axis. This case report details the successful treatment of recurrent nonobstructive cholangitis following a single FMT application in a patient who had previously undergone a hepatobiliary tract surgical diversion. Cholangitis was suspected secondary to reflux of an altered microbiome into the surgically reanastomosed biliary tract, and FMT was justified based on the history of recurrent Clostridioides difficile infections. This case supports the further evaluation of the utility of FMT as one potential treatment of post hepatobiliary surgical diversion cholangitis.

Source: ACG Case Reports Journal

DOI: 10.14309/crj.0000000000001527

Authors: Adam Scott, Alexander Khoruts, Martin L. Freeman, Greg Beilman, Karthik Ramanathan, Melena D. Bellin, Guru Trikudanathan

Institutions: University of Minnesota, University of Minnesota Medical Center

Language: English

Topic: Gallbladder and Bile Duct Disorders

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4403319416

FWCI: 1.81

Cites: 17

Cited by: 7

Related to: 10