Work

Skeletal Muscle Oxidative Metabolism during Exercise Measured with Near Infrared Spectroscopy

Year: 2024

Type: article

Abstract: This study characterized the level of oxidative metabolism in skeletal muscle during whole-body activity as a percentage of the muscle’s maximum oxidative rate (mVO2max) using near-infrared spectroscopy (NIRS). Ten healthy participants completed a progressive work test and whole-body walking and lunge exercises, while oxygen saturation was collected from the vastus lateralis muscle using near-infrared spectroscopy (NIRS). Muscle oxygen consumption (mVO2) was determined using arterial occlusions following each exercise. mVO2max was extrapolated from the mVO2 values determined from the progressive exercise test. mVO2max was 11.3 ± 3.3%/s on day one and 12.0 ± 2.9%/s on day two (p = 0.07). mVO2max had similar variation (ICC = 0.95, CV = 6.4%) to NIRS measures of oxidative metabolism. There was a progressive increase in mVO2 with walking at 3.2 Km/h, 4.8 km/h, 6.4 Km/h, and with lunges (15.8 ± 6.6%, 20.5 ± 7.2%, 26.0 ± 6.6%, and 57.4 ± 15.4% of mVO2max, respectively). Lunges showed a high reliability (ICC = 0.81, CV = 10.2%). Muscle oxidative metabolism in response to whole-body exercise can be reproducibly measured with arterial occlusions and NIRS. This method may be used to further research on mitochondrial activation within a single muscle during whole-body exercise.

Source: NDT

DOI: 10.3390/ndt2040025

Authors: Kevin K. McCully, Sarah N. Stoddard, Mary Ann Reynolds, Terence E. Ryan

Institutions: University of Georgia, University of Florida

Language: English

Topic: Cardiovascular and exercise physiology

Subfield: Complementary and alternative medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,137