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Comparative Immunohistochemistry Study Of Expression Of E- Cadherin In Benign Prostatic Hyperplasia And Prostate Cancer

Year: 2024

Type: article

Abstract: Benign Prostatic Hyperplasia (BPH) and Prostate Cancer (PC ) are the most common diseases in men, especially in older men than 50 years old, BPH is a non-cancerous enlargement of the prostate as a result of the increased number of smooth muscle cells. Tumors can be benign (not cancerous), or malignant (cancerous), prostate cancer is the abnormal and random growth of cells in the prostate gland to the extent that it loses its shape and function. this study involved 120 samples of tissues taken from men suffering from benign and malignant tumours with ages ranging between (40- 85) years. For detection of the expression of E-cadherin in BPH and PC using immunohistochemistry (IHC) method. The results obtained after microscopic examination showed that protein expression of E-cadherin was highly positive in BPH comparison with the expression of E-cadherin was weakly positive in low-grade cancer and negative in high-grade cancer (advanced prostate cancer).

Source: South Eastern European Journal of Public Health

DOI: 10.70135/seejph.vi.1505

Authors: Taghreed Hatem Khamees, Alaa Mohammad Hasson Al-Husseini, Aws Rassol Hussein

Institution: University of Al-Qadisiyah

Language: English

Topic: Prostate Cancer Treatment and Research

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4403359828

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