Work

‘Transparent mice’: deep-tissue live imaging using food dyes

Year: 2024

Type: article

Abstract: Light scattering, resulting from refractive index mismatch, is the primary factor limiting imaging depth in biological tissue. In a study recently published in Science1, Ou et al. took an unconventional approach and employed highly absorbing molecules, such as food dye tartrazine, to increase the refractive index of water in the near-infrared wavelength range, which rendered tissue transparent in live mice.

Source: Communications Biology

DOI: 10.1038/s42003-024-07012-9

Authors: Fei Wang, Chao Zhou

Institution: Washington University in St. Louis

Language: English

Topic: Optical Imaging and Spectroscopy Techniques

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

Open Access status: gold

Estimated APC paid: $3,890

OpenAlex ID: W4403362405