Work

Highly chemoselective and regiospecific Rh-catalyzed single-step hydroformylation of biomass derived (R)-carvone

Year: 2024

Type: article

Abstract: An efficient protocol for the rhodium catalyzed single-step hydroformylation of renewable natural olefin , (R)-carvone was developed, obtaining the corresponding linear aldehyde as the major product. The system was found to be highly sensitive to even slight variations in the reaction conditions, which had a tendency to complicate itself through the formation of numerous byproducts; nonetheless, high conversion (99 %), yield (95 %) and chemoselectivity (96 %) toward the desired aldehyde were accomplished under the optimized conditions. Moreover, this process proved to be regiospecific as no branched aldehyde was formed. These results were achieved by a careful tuning of different parameters such as temperature, pressure, reaction time, catalyst to ligand ratio, catalyst to substrate ratio and types of catalyst precursors, ligands and solvents.

Source: Molecular Catalysis

DOI: 10.1016/j.mcat.2024.114607

Authors: Rupali S. Prajapati, Bhalchandra M. Bhanage

Institution: Institute of Chemical Technology

Language: English

Topic: Asymmetric Hydrogenation and Catalysis

Subfield: Inorganic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: hybrid

Estimated APC paid: $3,110

Funders: Department of Science and Technology, Ministry of Science and Technology, India, University Grants Commission