Is there an association between daylight hours and serum testosterone levels in men?
Year: 2024
Type: article
Study design: Observational Study
Abstract: BACKGROUND: Studies assessing variability of serum testosterone levels associated with seasonal environmental factors have been contradictory. DESIGN: We assessed associations between the seasons and changes (δ) in seasonality indices and male serum total testosterone (δTT) variability. PATIENTS AND MEASUREMENTS: Data were collected in 144 men with paired serum TT samples (126 non-fasting/18 fasting) analysed at Walsall Manor Hospital, UK (52.3 degrees North). Seasonal factors (ambient temperature within 15 min of sampling, humidity, precipitation, duration of daylight on the day of sampling, monthly average ambient temperature, and precipitation) were obtained from local weather-station archives. Sign-rank test determined inter-sample differences between TT and seasonality indices. Linear regression analyses studied associations between δTT and δ seasonal indices in the total cohort and subgroups (stratified by medians of age, TT and men with paired non-fasting samples). Sign-rank determined whether serum TT differed between the seasons. RESULTS: = 0.032) were inversely associated with δTT in the 126 men in the non-fasting group (dependent variable). Only a small degree of the variability in the δTT was accounted by the above-mentioned independent variables. The seasons did not appear to influence serum TT values. CONCLUSIONS: No relation was shown between seasonality and serum TT in the total cohort, thus possibly eliminating a confounding variable that could affect laboratory and clinical practice. It may be that seasonal variation in length of day is too modest at this latitude to demonstrate significant associations, hence our findings are latitude specific. We suggest that further data analysis to address this question in areas with greater seasonal variation would be appropriate.
Source: The Aging Male
Institutions: University of Wolverhampton, Walsall Manor Hospital, Manchester Academic Health Science Centre, University of Manchester, Salford Royal Hospital, Aston University, University of East Anglia, University Hospitals Birmingham NHS Foundation Trust, University of Staffordshire, University Hospitals of North Midlands NHS Trust, Keele University, Brunel University of London
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,557
OpenAlex ID: W4403376328