Work

Effect of dexmedetomidine combined with ropivacaine block on flap blood flow and patient satisfaction after flap transfer for hand trauma: a randomized controlled trial

Year: 2024

Type: article

Study designs: Randomized Controlled Trial, Clinical Trial

Abstract: The purpose of this study was to assess the effect of dexmedetomidine as a local anaesthetic adjuvant on flap blood flow and patient satisfaction regarding postoperative analgesia anterolateral thigh free flap transfer for hand trauma. A total of 66 patients were randomized into two groups. One group was treated with intermittent 1.0 µg/mL dexmedetomidine + 0.125% ropivacaine bolus at 8 mL/2 h and the other with intermittent 0.2% ropivacaine bolus at 8 mL/2 h, administered via continuous infraclavicular brachial plexus block. Dexmedetomidine had no significant effect on the flap blood supply and had a good safety profile. Moreover, 1.0 µg/mL dexmedetomidine + 0.125% ropivacaine provided similar satisfactory postoperative analgesia as 0.2% ropivacaine ( p > 0.05), reduced hand numbness and motor block, and improved patient satisfaction ( p < 0.05). All the flaps in the dexmedetomidine + ropivacaine group and 30 of 31 flaps in the ropivacaine group survived. The addition of dexmedetomidine to the local anaesthetic infusion appears to be a safe method of improving postoperative symptoms. Level of evidence: I

Source: Journal of Hand Surgery (European Volume)

DOI: 10.1177/17531934241281649

Authors: Jinsong Zhao, Xionghui Kong, Zhou Zheng, Peijun Lv, Yeying Ge, Jian Huang

Institution: Ningbo No.6 Hospital

Language: English

Topic: Anesthesia and Pain Management

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,950