Work

Antimicrobial Activity of Amino-Modified Cellulose Nanofibrils Decorated with Silver Nanoparticles

Year: 2024

Type: article

Abstract: The silver nanoparticles (Ag NPs) conjugated with amino-functionalized cellulose nanofibrils (NH2 − CNFs) were in situ prepared by reducing silver ions with free amino groups from NH2 − CNFs. The spectroscopy and transmission electron microscopy measurements confirmed the presence of non-agglomerated nanometer-in-size Ag NPs within micrometer-large NH2 − CNFs of high (20 wt.-%) content. Although the consumption of amino groups during the formation of Ag NPs lowers the ζ-potential and surface charge of prepared inorganic-organic hybrids (from + 31.3 to + 19.9 mV and from 2.4 to 1.0 mmol/g at pH 7, respectively), their values are sufficiently positive to ensure electrostatic interaction with negatively charged cell walls of pathogens in acidic and slightly (up to pH ~ 8.5) alkaline solutions. The antimicrobial activity of hybrid microparticles against various pathogens (Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Candida albicans) is comparable with pristine NH2 − CNFs. However, a long-timescale use of hybrids ensures the slow and controlled release of Ag+ ions to surrounding media (less than 1 wt.-% for one month).

Source: Journal of Functional Biomaterials

DOI: 10.3390/jfb15100304

Authors: Vesna Lazic, Jovan M. Nedeljković, Vanja Kokol

Institutions: University of Belgrade, Vinča Institute of Nuclear Sciences, University of Maribor

Language: English

Topic: Advanced Cellulose Research Studies

Subfield: Biomaterials

Field: Materials Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,069