Work

Intrathecal baclofen obviating the need for bladder stimulator use in a patient with secondary dystonia: illustrative case

Year: 2024

Type: article

Abstract: BACKGROUND: Children with cerebral palsy often have neurogenic bladders. Bladder function is further affected by complex medical management and multifactorial disease processes, leading to worsened function and poorer quality of life. Intrathecal baclofen (ITB) therapy has been used to treat hypertonia and spasticity, but implications in neurogenic bladder management have not been well described. OBSERVATIONS: A 20-year-old female with a history of cerebral palsy and neurogenic bladder treated with sacral neuromodulation underwent ITB therapy and subsequently experienced improvement in bladder control, obviating the need for bladder stimulator use. LESSONS: ITB improves hypertonia and can effectively obviate the need for neurostimulation to treat neurogenic bladder in patients with cerebral palsy. Further research is necessary to discern mechanisms. https://thejns.org/doi/10.3171/CASE24364.

Source: Journal of Neurosurgery Case Lessons

DOI: 10.3171/case24364

Authors: Ryan K Wang, Victoria Jane Horak, Sunny Abdelmageed, Melissa A LoPresti, Maryam N Shahin, Benjamin Katholi, Jeffrey S Raskin

Institutions: Rosalind Franklin University of Medicine and Science, Lurie Children's Hospital, Northwestern University, University of Rochester Medicine, University of Rochester, Oregon Health & Science University, Shirley Ryan AbilityLab

Language: English

Topic: Urinary Bladder and Prostate Research

Subfield: Urology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4403384897

FWCI:

Cites: 30

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Related to: 10