Determining Predictive Power of Base Excess in Comparison with SOFA Score for Predicting Mortality in ICU Patients
Year: 2024
Type: article
Study design: Observational Study
Abstract: Background: Acid-base disturbances are frequently found in intensive care unit (ICU) patients. Base excess (BE) is commonly used to quantify the degree of metabolic impairment. We aimed to compare the predictive value of BE and Sequential Organ Failure Assessment (SOFA) score for mortality in ICU patients. Methods: This prospective and observational investigation was performed on 87 ICU patients who underwent mechanical ventilation. SOFA score and acid-base variables at 6 hours of ICU admission were analyzed and compared between survivors and non-survivors. Receiver-operating characteristic (ROC) curve was applied to analyze the predictive value of BE and SOFA for mortality. Results: = 0.002). The estimated AUC of SOFA and BE was 0.83 (95% CI, 0.73 - 0.92) and 0.71 (95% CI, 0.57 - 0.85), respectively. Conclusion: BE is, to some extent capable of predicting mortality in ICU patients. However, the SOFA score is a more accurate and reliable parameter in comparison to BE for prediction.
DOI: 10.47176/mjiri.38.74
Authors: Omid Moradi Moghaddam, Mohammajavad Gorjizadeh, Mohsen Sedighi, Alireza Amanollahi, Ali Khatibi, Mohammadreza Ghodrati, Mohammad Niakan Lahiji
Institution: Iran University of Medical Sciences
Language: English
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4403405834