Discovering bioactive phytoconstituents from Citrullus lanatus for antimicrobial and antioxidants therapeutic applications
Year: 2024
Type: article
Abstract: In recent decades, significant interest in natural bioactive compounds has led many researchers to study plants as primary natural sources of bioactive compounds, mainly when considering a few biological properties, including antioxidant, antimicrobial, and anti-inflammatory activities, and as nutritional supplements with health benefits. We designed this study to explore the phytochemicals profiling of Citrallus lanatus and evaluate their in vitro bioactive properties . The methanol extraction of the watermelon's stem, rind, and leaf parts through Soxhlet extraction was analyzed using Gas Chromatography-Mass Spectrometry. The GC-MS profiling of Citrullus lanatus examines the presence of numerous bioactive phytoconstituents with potential biological activities such as antioxidant, anti-inflammatory, antimicrobial, anticancer, and other properties. We have evidenced that the stem, rind, and leaf extracts with significant antioxidant and antimicrobial activities against clinically relevant pathogens like Salmonella typhi , Pseudomonas aeruginosa , Bacillus subtilis , and Staphylococcus aureus . Overall, our study sheds light on exploring novel bioactive phytoconstituents from C itrullus lanatus and explore, harness these compounds' therapeutic potential for human health.
Authors: Lakshmana Nakkalagadda Venkataravana, Jagadesh Uppin, Nikhitha Chinna Ramanjineyulu, Poojitha Gowribidanur Krishna, Jayaram Lakshmaiah Narayana
Language: English
Topic: Medicinal Plant Research
Subfield: Plant Science
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $1,500
OpenAlex ID: W4403411322