Work

Supplementary Figure S2 from Proportional Hazards Violations in Phase III Cancer Clinical Trials: A Potential Source of Trial Misinterpretation

Year: 2024

Type: supplementary-materials

Abstract: Figure S2. Scatterplot of the reported hazard ratio based upon reconstructed data compared to the trial’s reported hazard ratio for accurate and inaccurate reconstructions (N = 384). Trials were considered accurate if the absolute value of the ratio of the natural logarithm of the reported reconstructed hazard ratios was less than 0.1, while those with values equal to or greater than 0.1 were considered inaccurate and excluded prior to analysis.

DOI: 10.1158/1078-0432.27231430

Authors: Timothy A. Lin, Zachary R. McCaw, Alex Koong, Christine Lin, Joseph Abi Jaoude, Roshal Patel, Ramez Kouzy, Molly B. El Alam, Alexander D. Sherry, Sonal S. Noticewala, Clifton D. Fuller, Charles R. Thomas, Ryan Sun, J. Jack Lee, Ruitao Lin, Ying Yuan, Yu Shyr, Tomer Meirson, Ethan B. Ludmir

Language: English

Topic: Statistical Methods in Clinical Trials

Subfield: Statistics and Probability

Field: Mathematics

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4403436924

Cites:

Cited by:

Related to: 10