Work

Development of the SupersonicIEF Method for High‐Throughput Charge Variant Analysis

Year: 2024
Type: article
Abstract: The analysis of biopharmaceuticals for charge variants occurs from early-stage samples through formulation and process-development optimization. Higher throughput methods allow increased analysis of these samples to facilitate greater understanding of the samples and to better optimize their production and formulation. To enable higher throughput charge variant analysis, a new, rapid platform imaged capillary isoelectric focusing (icIEF) method was optimized to be two to three times faster than standard methods.
Language: English
Open Access status: hybrid
Estimated APC paid: $3,920
OpenAlex ID: W4403439462
FWCI: 0.426
Cites: 14
Cited by: 4
Related to: 10