A Case of Resectable Single-Nodule Intrahepatic Bile Duct Adenoma
Year: 2024
Type: article
Study design: Case Report
Abstract: A 70-year-old man was incidentally diagnosed with a single hepatic mass lesion in his right hepatic lobe during a computed tomography scan. The lesion exhibited consistent enhancement with contrast agents on computed tomography (CT), magnetic resonance imaging (MRI), and hepatic arterial angiography. While a definitive diagnosis could not be made preoperatively, the lesion was surgically resected due to its slight enlargement over two months, suggesting a potential malignancy. Pathological examination revealed the lesion to be a bile duct adenoma (BDA). The BDA was characterized by dense proliferative small gland cavities containing several to dozens of cells. Immunohistochemical staining showed positive CK7 and negative p53. The patient remains alive and free of recurrence five years after hepatectomy. Although BDAs are rare benign hepatic tumors, they carry a risk of harboring or developing malignant tissue, such as cholangiocarcinoma. Therefore, BDAs or lesions suspicious of BDA should be surgically resected or closely monitored.
Source: Cureus
DOI: 10.7759/cureus.71656
Authors: Hiroshi Okano, Hiroki Asakawa, Katsumi Mukai, Akira Nishimura, Takashi Hamada, Kana Asakawa, Youichirou Baba, Tetsuya Murata
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4403458982