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Role of intestinal glucagon-like peptide-1 in hypoglycemia response impairment in type 1 diabetes

Year: 2024

Type: article

Abstract: , which explores the role of intestinal glucagon-like peptide-1 (GLP-1) in impaired counterregulatory responses to hypoglycemia in mice with type 1 diabetes. The study identifies intestinal GLP-1 as a significant determinant in the physiological responses to hypoglycemia, offering new insights into its potential implications for diabetes management. The editorial synthesizes these findings, discusses their relevance in the context of current diabetes research, and outlines potential avenues for future investigation of intestinal GLP-1 as a therapeutic target. This analysis underscores the need for continued research into the complex mechanisms underlying impaired hypoglycemia responses and highlights the potential of targeting intestinal GLP-1 pathways in therapeutic strategies for type 1 diabetes.

Source: World Journal of Diabetes

DOI: 10.4239/wjd.v15.i11.2237

Authors: Chun-Han Cheng, Wen-Rui Hao, Tzu-Hurng Cheng

Institutions: Linkou Chang Gung Memorial Hospital, Ministry of Health and Welfare, Taipei Medical University-Shuang Ho Hospital, Taipei Medical University, China Medical University

Language: English

Topic: Diabetes Management and Research

Subfield: Endocrinology, Diabetes and Metabolism

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4403475512