Year: 2024
Type: article
Study design: Case Report
Abstract: Edwardsiella tarda is frequently isolated from aquatic animals and environments. While human infections caused by E. tarda are rare, some extraintestinal infections can be severe. This case report describes a patient with cellulitis of the right upper extremity of unknown origin. Metagenomic next-generation sequencing (mNGS) indicated that the patient was infected with E. tarda . Antimicrobial susceptibility testing revealed that the isolate was resistant to quinolones and trimethoprim/sulfamethoxazole. The isolate, positive for four virulence genes ( fimA, gadB, mukF , and sodB ), was confirmed to be virulent using the Galleria mellonella larvae model. Following early pus drainage and a 9-day course of imipenem, the patient ultimately recovered. This case report aimed to illustrate the presentation, diagnosis, and management of uncommon cellulitis caused by drug-resistant, virulent E. tarda .
Source: Frontiers in Medicine
Authors: Xuejin Wang, Danxia Gu, Liwei Zhang, Yuchen Wu, Rong Zhang, Kewei Li, Haitao Ren
Language: English
Subfield: Endocrinology
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $3,295
Awards: G1793344323, G3609057288, G4349479772
OpenAlex ID: W4403476020