Work

Teratogenic effect of Misoprostol following failure of elective abortion: A case of femoral agenesis and review of the literature

Year: 2024

Type: article

Abstract: Misoprostol, a synthetic analogue of prostaglandin E1, is commonly used in gynecology, particularly in combination with mifepristone for elective abortion. Although its use is widespread, the potential teratogenic effects of misoprostol in cases of failed medical abortion have not been sufficiently explored in the medical literature. Severe congenital malformations, although rare, have been reported, raising concerns about the impact of this drug on fetal development. We present a rare case of femoral agenesis observed in a woman who experienced a failed medical abortion with Misoprostol (Cytotec®), highlighting the need for a better understanding of the risks associated with fetal exposure to this drug and the implementation of rigorous follow-up measures after its use.

Source: Radiology Case Reports

DOI: 10.1016/j.radcr.2024.09.133

Authors: Hiba Ben Abdelhafidh, Oumayma Ben Rejeb, Nour Rouis, Badra Bannour, Neila Fathallah, Imen Bannour

Institutions: Hôpital Farhat Hached, University of Sousse

Language: English

Topic: Reproductive Health and Contraception

Subfield: Public Health, Environmental and Occupational Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $550