Work

Fibrofolliculomas in Birt-Hogg-Dubé syndrome treated with a CO2 and dye laser combination: a case report and literature review

Year: 2024

Type: article

Abstract: Birt-Hogg-Dubé syndrome (BHD) can cause benign skin lesions such as fibrofolliculomas, as well as systemic manifestations including pulmonary cysts, kidney tumors, and recurrent pneumothoraces. We report the successful treatment of fibrofolliculomas in a patient with BHDs using a combination of fractionated ablative CO2 laser and a flash lamp pulsed dye laser (FPDL). This combined method improves the CO2 healing process's functional and cosmetic results; the first wavelength (ablative) has a greater capacity for excision and tissue regeneration, while the second (non-ablative) provides more control over the tissue healing process. The lesions were ablated up to the papillary dermis without enhancing the overall textural appearance. Therefore, deeper laser ablations may be able to stop dermal residual lesion relapses. In conclusion, fractionated CO2 laser and FPDL can be used safely and effectively to reduce the appearance of facial hamartomas related to BHDs.

Source: Dermatology Reports

DOI: 10.4081/dr.2024.10066

Authors: Giuseppe Lodi, Giovanni Cannarozzo, Mario Sannino, Laura Pieri, Irene Fusco, Francesca Negosanti

Institutions: University of Campania "Luigi Vanvitelli", University of Rome Tor Vergata, El.En. Group (Italy)

Language: English

Topic: Dermatologic Treatments and Research

Subfield: Dermatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $539