Work

The Pouch Corner: Perianal Fistulas and Ileal Pouches: Examining Fistulas Before and After Pouch Creation

Year: 2024

Type: article

Abstract: Lay Summary Patients with ulcerative colitis (UC) and Crohn’s disease (CD) proctocolitis are candidates for an ileal pouch-anal anastomosis (IPAA), provided they do not suffer from complex perianal fistulas or small bowel inflammation. UC patients who develop a simple perianal fistula may still be candidates for an IPAA; however, patients with complex perianal fistulas are precluded from having an ileal pouch. After an IPAA, patients may develop perianal fistulas that arise acutely from a technical complication or an anastomotic leak, or as late-onset fistulas as a result of CD-like inflammation of the pouch.

Source: Inflammatory Bowel Diseases

DOI: 10.1093/ibd/izae205

Authors: David M Schwartzberg, Maia Kayal, Edward L Barnes

Institutions: Northwell Health, Icahn School of Medicine at Mount Sinai, University of North Carolina at Chapel Hill

Language: English

Topic: Inflammatory Bowel Disease

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases