Work

The human claustrum tracks slow waves during sleep

Year: 2024

Type: article

Abstract: Slow waves are a distinguishing feature of non-rapid-eye-movement (NREM) sleep, an evolutionarily conserved process critical for brain function. Non-human studies posit that the claustrum, a small subcortical nucleus, coordinates slow waves. We recorded claustrum neurons in humans during sleep. In contrast to neurons from other brain regions, claustrum neurons increased their activity and tracked slow waves during NREM sleep suggesting that the claustrum plays a role in human sleep architecture.

Source: Nature Communications

DOI: 10.1038/s41467-024-53477-x

Authors: Layton Lamsam, Brett Gu, Mingli Liang, George Sun, Kamren J. Khan, Kevin N. Sheth, Lawrence J. Hirsch, Christopher Pittenger, Alfred P. Kaye, John H. Krystal, Eyiyemisi C. Damisah

Institution: Yale University

Language: English

Topic: Sleep and Wakefulness Research

Subfield: Cognitive Neuroscience

Field: Neuroscience

Domain: Life Sciences

Open Access status: gold

Estimated APC paid: $6,790

Funders: Yale University, National Institutes of Health, National Heart, Lung, and Blood Institute, National Institute of Mental Health, National Center for Advancing Translational Sciences

Awards: G1044130170, G330629187, G6851913581, G7007213828, G846228670, G9000041528, G9000242664, Yale Clinical and Translational Science Award, J. NRSA Training Core, G945977467

OpenAlex ID: W4403513290

FWCI: 3.9

Cites: 64

Cited by: 17

Related to: 10