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Chemotherapy Sparks Tertiary Lymphoid Structures in Metastatic Ovarian Cancer

Year: 2024
Type: article
Abstract: Ovarian cancer remains resistant to immunotherapy in most patients, highlighting the need to make these tumors more immunogenic. A recent study unveils how chemotherapy is able to induce cancer cell stress in metastatic ovarian carcinomas, inducing the formation of tertiary lymphoid structures that create a "hotter" tumor microenvironment. See related article by Lanickova et al., p. 164.
Language: English
Subfield: Oncology
Field: Medicine
Open Access status: green
OpenAlex ID: W4403519644
FWCI: 0.312
Cites: 7
Cited by: 2
Related to: 10