Year: 2024
Type: article
Abstract: Ovarian cancer-What is the clinical need to be addressed?Multidisciplinary working is the cornerstone for optimal management of ovarian cancer with radiological assessment crucial throughout the patient pathway.Ovarian cancer is a term that encompasses pathologically distinct malignancies, all of which can have different patterns of spread and responses to treatment.The most common type of ovarian cancer arises from the epithelial cells of the fallopian tubes and ovaries (epithelial ovarian cancer, EOC); rarer subtypes and those arising from non-epithelial cells include ovarian germ cell tumours, ovarian stromal tumours and small cell carcinoma of the ovary.Management of all ovarian cancers is centred around combining surgical approaches with systemic anti-cancer treatment.Increased understanding of the biology and genomic makeup of ovarian cancer together with enhanced surgical techniques and more targeted treatments has led to paradigm shifts in the way that the disease is managed.Despite these advances, EOC continues to be the most lethal gynaecological malignancy responsible for over 200,000 deaths per year worldwide [1].There is no effective population screening.Ovarian cancer is associated with non-specific symptoms and many women present late with advanced disease.There is an unmet need for earlier detection, novel and more targeted treatments and a better understanding of the development of treatment resistance.
Source: European Radiology
Authors: Stacey Bryan, Andrea Rockall, Laura Tookman
Language: English
Subfield: Reproductive Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $4,190
OpenAlex ID: W4403523620