Work

Load-dependent mechanisms contribute to increased aortic stiffness among women with a history of preeclampsia: relation with cardiovagal baroreflex sensitivity

Year: 2024

Type: article

Study design: Observational Study

Abstract: The novel finding is that load-dependent stiffness, not structural stiffness, is the primary mechanism of aortic stiffness, and is associated with reduced baroreflex sensitivity in women with a history of preeclampsia. These findings may help tailor high blood pressure prevention and management strategies in this population to prevent structural aortic stiffening, altered baroreflex control, and increased lifetime cardiovascular disease (CVD) risk.

Source: American Journal of Physiology-Heart and Circulatory Physiology

DOI: 10.1152/ajpheart.00556.2024

Authors: Kristen G. Davis, Matthew K. Armstrong, Virginia R. Nuckols, Meaghan N. Smith, Ryan Pewowaruk, Colin J. Gimblet, Donna A. Santillan, Mark K. Santillan, Gary L. Pierce

Institution: University of Iowa

Language: English

Topic: Cardiovascular Health and Disease Prevention

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: American Heart Association, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, National Center for Advancing Translational Sciences, Eunice Kennedy Shriver National Institute of Child Health and Human Development

Awards: G1275489003, Cognitive Function and Brain Structure Early Postpartum in Women with Preeclampsia, Mechanisms of Early and Late Postpartum Hypertension in Human Preeclampsia, Iowa Training Program in Kidney and Hypertension Research, G7259054382, G9000181048

OpenAlex ID: W4403536489

FWCI: 1.603

Cites: 42

Cited by: 6

Related to: 10