Work

Synthesis and biological evaluation of novel D-ring fused steroidal N (2)-substituted-1,2,3-triazoles

Year: 2024

Type: article

Abstract: (2)-substituted-1,2,3-triazoles are high-affinity ligands for estrogen receptor β and glucocorticoid receptor, inhibitors of aldo-keto reductase 1C3 enzyme, and exhibit antiproliferative effects against cancer cells, suggesting that they could serve as scaffolds for anticancer drug development.

Source: RSC Medicinal Chemistry

DOI: 10.1039/d4md00297k

Authors: Branislava Tenjović, Sofija Bekić, Andjelka Ćelić, Edward Petri, Julia Scholda, Florian Kopp, Marija Sakač, Andrea Nikolić

Institutions: University of Novi Sad, University of Vienna

Language: English

Topic: Synthesis and biological activity

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green

Funder: Provincial Secretariat for Higher Education and Scientific Research, Autonomous Province of Vojvodina

Award: G2927790069

OpenAlex ID: W4403538052

FWCI: 1.395

Cites: 70

Cited by: 10

Related to: 10