Work

Hepatic peliosis in a newborn - A case report and review of the literature

Year: 2024

Type: article

Abstract: INTRODUCTION: Hepatic peliosis is a rare benign vascular disorder characterized by dilatation of sinusoidal blood-filled spaces within the liver. It often remains asymptomatic and is diagnosed incidentally in an autopsy. Herein, we report a case of a 1-day-old female newborn who was admitted to the neonatal resuscitation unit for abdominal distension. CASE PRESENTATION: An abdominal examination revealed a firm mass with irregular contours in the upper quadrant of the abdomen, indicating hepatomegaly. Radiological explorations confirmed the hepatomegaly, and an ultrasound-guided liver biopsy showed the presence of multiple blood cavities with sinusoidal dilation typical of hepatic peliosis. DISCUSSION: None of the known risk factors were found in this case except antihistaminic drug consumption during pregnancy by the mother, which could possibly have a link, although never described. CONCLUSION: In this article, we report a case of neonatal hepatic peliosis likely secondary to antihistaminic consumption during pregnancy. To the best of our knowledge, this is the fifth reported case (based on the MEDLINE, Scopus, and Google Scholar databases) of neonatal hepatic peliosis.

Source: International Journal of Surgery Case Reports

DOI: 10.1016/j.ijscr.2024.110476

Authors: Wahib Lahlou, Abderrahim Bourial, Amal Rami, Abderrahmane Al Bouzidi, Mouad Nejjari, Inssaf Alammari

Institutions: Université Mohammed VI des Sciences et de la Santé, Hôpital Universitaire International Cheikh Khalifa

Language: English

Topic: Vascular Malformations and Hemangiomas

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,800