Work

Recurrent perforation of an implantable cardioverter-defibrillator lead in a patient with vascular Ehlers-Danlos syndrome

Year: 2024

Type: article

Abstract: Vascular Ehlers-Danlos Syndrome (vEDS) is a rare genetic connective tissue disorder with an estimated prevalence of 1:100,000 to 1:200,000.1 It is caused by heterozygous pathogenic variants of the COL3A1 gene encoding type III collagen. vEDS is phenotypically characterized by thin, translucent, and easily bruised skin and fragile blood vessels and organs, leading to arterial dissections or ruptures, spontaneous gastrointestinal perforations, and urogenital perforations, notably including uterine rupture during pregnancy or childbirth.

Source: HeartRhythm Case Reports

DOI: 10.1016/j.hrcr.2024.10.015

Authors: Kyuna Lee, Steven Liskov, Neal K. Lakdawala, Gretchen MacCarrick, Harry C. Dietz, Andreas S. Barth

Institutions: Johns Hopkins University, Johns Hopkins Medicine, Brigham and Women's Hospital, Harvard University

Language: English

Topic: Cardiac pacing and defibrillation studies

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,100