Bioassay protocol metadata annotation: Proposed standards adoption
Year: 2024
Type: article
Abstract: We present a standardized metadata template for assays used in pharmaceutical drug discovery research, according to the FAIR principles. We also describe the use of an automated tool for annotating assays from a variety of sources, including PubChem, commercial assay providers, and the peer-reviewed literature, to this metadata template. Adoption of a standardized metadata template will allow drug discovery scientists to better understand and compare the increasing amounts of assay data becoming available, and will facilitate the use of artificial intelligence tools and other computational methods for analysis and prediction. Since bioassays drive advances in biomedical research, improvements in assay metadata can improve productivity in discovery of new therapeutics, platform technologies, and assay methods.
Source: SLAS DISCOVERY
Authors: Rama Balakrishnan, Ellen L. Berg, Christopher C. Butler, Alex M. Clark, Sheryl P. Denker, Isabella Feierberg, Jason Harris, Timothy P. Ikeda, Samantha Jeschonek, Vladimir A. Makarov, Christopher Southan, Dana Vanderwall, Peter Winstanley
Language: English
Subfield: Information Systems
Field: Computer Science
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $1,800
OpenAlex ID: W4403559264