Work

Pharmacokinetics of the drug Amoxyantar in pigs

Year: 2024

Type: article

Abstract: The article presents the results of pharmacokinetic studies of the drug Amoxiyantar in pigs. The results obtained indicate that amoxicillin is distributed throughout the tissues of animals, providing therapeutic concentrations in the studied dosage, ensuring effective distribution in the organs and tissues of the body of pigs, and also confirm the bioavailability of succinic acid with a high concentration in the blood plasma for an average of two hours. Based on the results of determining the dynamics of excretion of residual amounts of amoxicillin, it was detected in only one animal in the kidneys at a concentration of 54.9 μg/kg and in muscle tissue at a concentration of 25.2 μg/kg. In the remaining tissue samples of pigs obtained two days after application of the drug, as well as in all tissue samples of pigs obtained from the sixth day to the 18th day after application of the drug, amoxicillin was not detected.

Source: Legal regulation in veterinary medicine

DOI: 10.52419/issn2782-6252.2024.3.98

Authors: S. V. Engashev, A. A. Komarov, A. M. Lunegov, A. S. Khlebalina

Institutions: Moscow State University of Food Production, Saint Petersburg State University of Veterinary Medicine, All-Russian Scientific Research and Technological Institute of Poultry Russian Academy of Agricultural Sciences

Language: English

Topic: Antibiotics Pharmacokinetics and Efficacy

Subfield: Pharmacology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4403567936

FWCI:

Cites: 4

Cited by:

Related to: 10