Year: 2024
Type: article
Study design: Case Report
Abstract: SAPHO syndrome (synovitis, acne, pustulosis, hyperostosis, osteitis syndrome) is a systemic inflammatory disease characterized by a combination of both osteoarticular and dermatological manifestations. We encountered an interesting case of a 54-year-old female patient who presented with symptoms of recurrent chest infections. Extensive investigations, including laboratory tests and imaging, were conducted with an initial suspicion of malignancy, but the patient was ultimately diagnosed with SAPHO. Treatment was initiated with a corticosteroid and an immunosuppressant, resulting in mild symptom improvement. This case emphasizes the importance of considering SAPHO syndrome in patients with unexplained musculoskeletal and dermatological symptoms, as early diagnosis and treatment can significantly impact patient outcomes.
Source: Cureus
DOI: 10.7759/cureus.71897
Authors: Maryam Zahid, Varshini Vishwanatham, Iqra Nasir
Institution: Ninewells Hospital
Language: English
Subfield: Rheumatology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4403571250