Preclinical Evaluation of Polyherbal as an Anti- Alzheimers, by Using In-vitro Anticholinesterase Enzyme Model
Year: 2024
Type: article
Abstract: Background: Alzheimers disease is a neurodegenerative brain condition that causes mild cognitive impairment and memory loss, eventually leading to dementia. With developments in medicine, there are now more people in the world trying to treat a wider range of illnesses. It has been discovered that traditional herbal treatment works well with little or no adverse effects. Materials & Methods: There are certain chemical components in the polyherbal extract of liquorice, ginger, and hibiscus sabadariffa that have anti-Alzheimers properties. Results & Discussion: The polyherbal extract of liquorice, ginger, and hibiscus sabadariffa has been shown to have significant inhibition up to 44.02% in the group treated with it, which supports the extracts anti-Alzheimers activity. This was determined through a dose-dependent study and statistical comparison using Graph Pad Prism, version 10.2.2 by two-way ANOVA.
Authors: Somvanshi S.R., Talware P.R., Gaikwad Y.S., Patil R.N., Vyavhare P.V.
Language: English
Subfield: Complementary and alternative medicine
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4403607792