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Brief communication: coagulation profiles of HIV positive patients on antiretroviral therapy (ART) at the Mampong Municipal Hospital, Ashanti-Region, Ghana: a case control study

Year: 2024

Type: article

Abstract: This study aimed to ascertain how the current two ART regimens used in Ghana affected HIV patients' coagulation profiles. A case-control study was conducted on 102 HIV positive patients at the Mampong Municipal Hospital. Coagulation parameters measured showed APTT was normal in majority of ART-experienced participants but prolonged in majority of ART-naïve participants. The mean platelet count was significantly higher in ART-experienced participants. No significant differences were found between the coagulation profiles of ART-experienced patients on two different drug regimens. In conclusion, current ART can enhance the coagulation profiles in HIV-infected patients, by improving platelet count and APTT.

Source: AIDS Research and Therapy

DOI: 10.1186/s12981-024-00665-w

Authors: Freddie Boateng Opoku, Akua Koaso Yalley, Nicholas Israel Nii-Trebi, Ekoutiame Ahlin, Abena Asefuaba Yalley, Ransford Kyeremeh

Institutions: University of Ghana, University of Konstanz, Freie Universität Berlin

Language: English