Work

Design of Murine Double Minute 2 Proteolysis Targeting Chimera Degraders with a Built-In Tumor-Targeting Ability

Year: 2024

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.4c01228

Authors: Zhuqian Wang, Siran Yue, Xinxin Chen, Jin Li, Peixi Zhu, Hongzhen Chen, Fang Qiu, Duoli Xie, Yiying Liang, Defang Li, Aiping Lu, Chao Liang

Institutions: Hong Kong Baptist University, Southern University of Science and Technology, Binzhou Medical University, Shanghai University of Traditional Chinese Medicine, State Key Laboratory of Proteomics

Language: English

Topic: Protein Degradation and Inhibitors

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: National Natural Science Foundation of China, Research Grants Council, University Grants Committee, Science, Technology and Innovation Commission of Shenzhen Municipality, Basic and Applied Basic Research Foundation of Guangdong Province

Awards: G1753612344, G371944149, G4776882740, G5843463501, G5954605393, Development of combination therapy using a mCRP aptamer and Leflunomide for precision medicine-based rheumatoid arthritis treatment

OpenAlex ID: W4403624091

FWCI: 1.157

Cites: 53

Cited by: 10

Related to: 10