Unmasking the Origin of Cutaneous Metastasis: A Case Report
Year: 2024
Type: article
Study design: Case Report
Abstract: Cutaneous metastasis typically represents a late manifestation of internal malignancy. We present the case of a 60-year-old woman with a history of cervical cancer who presented with lower abdominal pain. Imaging studies revealed a high-grade carcinoma involving the urothelium, suggestive of primary urothelial carcinoma. Further investigation uncovered widespread metastatic disease, including cutaneous metastases to the arm and pelvis. Despite a comprehensive diagnostic workup, including immunohistochemical analysis, the primary tumor site could not be definitively identified, underscoring the challenges in diagnosing cutaneous metastases of unknown origin. This case highlights the necessity of considering metastatic disease in patients with atypical skin findings. Moreover, it emphasizes the aggressive nature of cutaneous metastases, particularly those originating from urothelial carcinomas, which are associated with a poor prognosis and limited treatment options.
Source: Cureus
DOI: 10.7759/cureus.72156
Authors: Paola Campillo, Adriana Morales Rivera, Alice Kesler, Zein Barakat, Ganga B Ramidi
Institution: Lakeland Regional Medical Center
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4403626295