Identifying adolescents with increased cardiometabolic risk—Simple, but challenging
Year: 2024
Type: article
Abstract: The prevalence of increased cardiometabolic risk, such as insulin resistance and type 2 diabetes, has increased worldwide in adolescents.1 Insulin resistance and type 2 diabetes in childhood and adolescence predict insulin resistance, type 2 diabetes, and preclinical atherosclerosis23 as well as retinal and kidney disease4 in adulthood. In addition to the individual-level burden of these diseases, the economic costs of type 2 diabetes are measured in billions of US dollars.56 Therefore, to counteract these adverse effects and increased economic burden, the early identification of children and adolescents with increased risk of insulin resistance and type 2 diabetes is essential. However, objective methods, such as fasting blood samples or glucose tolerance tests, may not be commonly available or feasible at, for example, school healthcare centers due to the costs and the lack of appropriately trained laboratory staff. Therefore, indirect, affordable, and feasible indicators helping to identify youth with increased risk of cardiometabolic diseases are warranted.
Source: Jornal de Pediatria
Author: Eero A. Haapala
Institutions: University of Eastern Finland, University of Jyväskylä
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $1,800
OpenAlex ID: W4403639372