Intestinal tuft cells act as reserve stem cells after injury
Year: 2024
Type: article
Abstract: The mechanisms that compensate for the loss of intestinal stem cells after injury are poorly defined. There is a population of intestinal cells, called tuft cells, that do not normally divide. When activated by immunological cues, these cells become proliferative and thus can act as a reserve stem-cell population. A population of cells in the gut can regenerate cell types when normal stem cells are lost.
Source: Nature
Language: English
Topic: IL-33, ST2, and ILC Pathways
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: hybrid
Estimated APC paid: $12,290
OpenAlex ID: W4403683601