Work

Foscarnet eyedrops for the treatment of refractory herpetic keratitis

Year: 2024

Type: article

Abstract: PURPOSE: The purpose of this case series is to describe the clinical course of patients receiving foscarnet eyedrops for the treatment of refractory herpetic keratitis. OBSERVATIONS: Six patients diagnosed with herpetic keratitis were treated with foscarnet 24 mg/mL (2.4%) eyedrops with resulting improvement in keratitis. CONCLUSION: Topical foscarnet may be a safe and effective treatment for herpetic keratitis in conjunction with, or as an alternative to, conventional antiviral therapy. This is an off-label use of foscarnet.

Source: Journal of Ophthalmic Inflammation and Infection

DOI: 10.1186/s12348-024-00395-0

Authors: Caroline C. Awh, Austen N. Knapp, Jeffrey M. Goshe, Craig W. See, Careen Y. Lowder

Institution: Cleveland Clinic

Language: English

Topic: Ocular Infections and Treatments

Subfield: Ophthalmology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,190