Synthesis of new triazole derivatives and their potential applications for removal of heavy metals from aqueous solution and antibacterial activities
Year: 2024
Type: article
Abstract: In this paper, triazole derivatives were prepared by a three-step mild reaction using carbon disulfide as starting material. In face of microbial threats, we found that compound 3-cyclopropyl-[1,2,4]triazolo [3,4-b][1,3,4]thiadiazole-6-thiol (C2) has good antibacterial activity, inhibition and clearance ability against biofilms, low hemolytic activity and toxicity, good anti-inflammatory activity. At the same time, we found that B and C series compounds have good metal ion scavenging ability, with removal rates of C series ranging from 47% to 67% and B series ranging from 67% to 87%.
Source: Frontiers in Chemistry
Authors: Chunyun Xu, Na Yang, Haichun Yu, Xiaojing Wang
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $3,295
OpenAlex ID: W4403701170