Work

Early synaptic dysfunction of striatal parvalbumin interneurons in a mouse model of Parkinson’s disease

Year: 2024

Type: article

Abstract: ) oscillation in the striatum of parkinsonian mice. Collectively, our findings underscore the vulnerability of PV interneurons to dopamine depletion and their responsibility for the evolution of abnormal activities in parkinsonian striatum.

Source: iScience

DOI: 10.1016/j.isci.2024.111253

Authors: Quansheng He, Xiaowen Zhang, Hongyu Yang, Dahui Wang, Yousheng Shu, Xuan Wang

Institutions: Fudan University, State Key Laboratory of Medical Neurobiology, Frontiers Center for Brain Science of the Ministry of Education, Beijing Normal University, Affiliated Hospital of Jiangsu University

Language: English

Topic: Parkinson's Disease Mechanisms and Treatments

Subfield: Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,150

Funders: National Natural Science Foundation of China, Ministry of Science and Technology of the People's Republic of China, China Postdoctoral Science Foundation, Program of Shanghai Academic Research Leader

Awards: G1992715655, G3334344442, G3970607251, G514510173, G5849529042, G6789192089, G7214881151

OpenAlex ID: W4403707614

FWCI: 1.834

Cites: 76

Cited by: 8

Related to: 10