Work

Decarboxylative Xanthylation under Photocatalytic Conditions

Year: 2024

Type: article

Abstract: Xanthates are widely used in organic synthesis for the construction of various molecules and have numerous applications as bioactive compounds. Here, we present their preparation via a straightforward photocatalytic decarboxylative xanthylation process involving readily available oxime esters and xanthate dimers. This approach provides access to a wide variety of xanthate compounds in moderate to good yields, including xanthates derived from relevant pharmaceutical and bioactive molecules.

Source: Organic Letters

DOI: 10.1021/acs.orglett.4c03616

Authors: Lilian Geniller, Céleste Souche, Marc Taillefer, Florian Jaroschik, Alexis Prieto

Institutions: École Nationale Supérieure de Chimie de Montpellier, Centre National de la Recherche Scientifique, Université de Montpellier, Institut Charles Gerhardt Montpellier

Language: English

Topic: Radical Photochemical Reactions

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

Funder: Agence Nationale de la Recherche

Award: Uniersité de Montpellier Graduate School