Work

Leflunomide-Induced Drug Reaction With Eosinophilia and Systemic Symptoms: A Diagnostic Dilemma

Year: 2024

Type: article

Abstract: Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a severe idiosyncratic drug reaction. This commonly manifests with fever, lymphadenopathy, and a maculopapular rash. It can be fatal if early diagnosis and removal of the offending agent do not occur. Leflunomide, a disease-modifying antirheumatic drug (DMARD) has been rarely associated with DRESS syndrome. Here, we present the case of a 59-year-old male patient admitted with leflunomide-induced DRESS syndrome.

Source: Cureus

DOI: 10.7759/cureus.72287

Authors: Anjali Jayakumar, Harikrishnan S, Tomy Philip, Meenu Rose Jomey

Institution: Pushpagiri Medical College

Language: English

Topic: Drug-Induced Adverse Reactions

Subfield: Pharmacology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4403731054