Work

Emergence of the stromal vascular fraction and secretome in regenerative medicine

Year: 2024

Type: article

Abstract: Recently, we read a mini-review published by Jeyaraman et al . The article explored the optimal methods for isolating mesenchymal stromal cells from adipose tissue-derived stromal vascular fraction (SVF). Key factors include tissue source, processing techniques, cell viability assessment, and the advantages/disadvantages of autologous vs allogeneic use. The authors emphasized the need for standardized protocols for SVF isolation, ethical and regulatory standards for cell-based therapy, and safety to advance mesenchymal stromal cell-based therapies in human patients. This manuscript shares our perspective on SVF isolation in canines. We discussed future directions to potentiate effective regenerative medicine therapeutics in human and veterinary medicine.

Source: World Journal of Stem Cells

DOI: 10.4252/wjsc.v16.i10.896

Authors: Ratan Kumar Choudhary, Shanti Choudhary, Abhishek Tripathi

Institution: Guru Angad Dev Veterinary and Animal Sciences University

Language: English

Topic: Mesenchymal stem cell research

Subfield: Genetics

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funder: Science and Engineering Research Board