Figure 3 from Prostate Cancer Progression Modeling Provides Insight into Dynamic Molecular Changes Associated with Progressive Disease States
Year: 2024
Type: other
Abstract: Enrichment analysis of T-stage and summary GS mapped onto four identified progression paths. A, T-stage. Tumor samples with T-stages 3 and 4 were plotted on the top (red), and those with T-stages 1 and 2 plotted at the bottom (black). B, Summary GS. Tumor samples with summary GS ≥ 4 + 3 were plotted on the top (red), and those with summary GS ≤ 3 + 4 plotted at the bottom (black). The x-axis represents the progression distances of tumor samples along a path, and P values were computed through 10,000 permutation tests. A negative enrichment score (defined as the maximum deviation of a running sum statistic from zero) indicates that T-stage ≥ 3 or GS ≥ 4 + 3 tumors were enriched at the end of a progression path, and a broken line indicates the location of the enrichment score on the progression path.
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4403733662