Work

Evidence of Clinical and Laboratory Correlation of Itraconazole Resistance in Sporothrix brasiliensis Infection: Case Report

Year: 2024

Type: article

Study design: Case Report

Abstract: Sporotrichosis is a subcutaneous infection caused by fungi from the genus Sporothrix, among which Sporothrix brasiliensis displays high virulence and transmissibility. So far, classical antifungal agents have been efficient against S. brasiliensis, but here we describe the first case of therapeutic failure and a high minimum inhibitory concentration (MIC) in relation to itraconazole.

Source: Microorganisms

DOI: 10.3390/microorganisms12112132

Authors: John Verrinder Veasey, Ana Paula Carvalho Reis, Giovanna Azevedo Celestrino, Camila Estacia Silva, Eduarda Souza Santos, Denise Polizel Mendes, Tania Sueli Andrade, Lucas Xavier Bonfietti, Gil Benard, Maria Glória Texeira Sousa

Institutions: Faculdade de Ciências Médicas da Santa Casa de São Paulo, Universidade de São Paulo, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Instituto Adolfo Lutz

Language: English

Topic: Fungal Infections and Studies

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,069

Funder: Fundação de Amparo à Pesquisa do Estado de São Paulo

Awards: G1004419944, G4524612451, G5150437167, G570223559, G6191138830, Chronic disseminated dermatophytosis due to Trichophyton rubrum: role of neutrophils in the effector mechanisms and in the modulation of the adaptive response of the human infection, G6867105699, G8424568053, G8814627206, Impact of immunosenescence on in vitro response of B lymphocytes of individuals vaccinated against COVID-19: influence of smoking and chronic obstructive pulmonary disease

OpenAlex ID: W4403734104

FWCI: 2.343

Cites: 14

Cited by: 9

Related to: 10