Work

Basophils: Regulators of lung inflammation over space and time

Year: 2024

Type: article

Abstract: In this issue of JEM, Schuijs et al. (https://doi.org/10.1084/jem.20240103) highlight a novel role for basophils during allergic immune responses to house dust mites (HDM). They reveal that interleukin-33 (IL-33)-activated basophils facilitate the recruitment and extravasation of Th2 cells into the lungs during a specific time frame via their interactions with pulmonary endothelial cells.

Source: The Journal of Experimental Medicine

DOI: 10.1084/jem.20241663

Authors: Régis Joulia, Clare M. Lloyd

Institution: Imperial College London

Language: English

Topic: IL-33, ST2, and ILC Pathways

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funders: Fondation Acteria, Wellcome Trust, European Federation of Immunological Societies