Work

Veratridine, a plant-derived alkaloid, suppresses the hyperactive Rictor-mTORC2 pathway: a new targeted therapy for primary and metastatic colorectal cancer

Year: 2024

Type: preprint

Source: Research Square

DOI: 10.21203/rs.3.rs-5199838/v1

Authors: Morgan M. Eikanger, Sanam Sane, Kate S. Schraufnagel, John L. Slunecka, Rashaun A. Potts, Jessica Freeling, Grigoriy Sereda, Bakhtiyor Rasulev, Reed L. Brockstein, M A Bashar Emon, M Taher A. Saif, Khosrow Rezvani

Institutions: University of South Dakota, North Dakota State University, University of Illinois Urbana-Champaign

Language: English

Topic: PI3K/AKT/mTOR signaling in cancer

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Institute of General Medical Sciences

Awards: UBXN2A represses migration and invasion of colorectal cancer cells, STARTUP Central, Dakota Cancer Collaborative on Translational Activity, "SMART" nanoparticle delivery of veratridine overcomes clinical challenges in metastatic colorectal cancer., Midwest Biomedical Accelerator Consortium: MBArC, Great Plains IDeA-CTR, Tissue microenvironment (TIMe) training program

OpenAlex ID: W4403749524

Cites: 80

Cited by: 3

Related to: 10