Work

Clonal distribution and molecular characterization of Staphylococcus aureus isolated strains in Chania and Heraklion, Crete

Year: 2024

Type: article

Abstract: Aim. This study investigates the demographic distribution, antibiotic resistance profiles, and molecular characteristics of Staphylococcus aureus infections. Methods. The study was carried out in 141 patients, 60.4% male, in patients from Chania and Heraklion, Crete. Results. The highest infection prevalence observed in the older adults (≥65 years) age group. The predominant infection types were skin lesions (39.72) and respiratory tract infection (22.7%). Antibiotic resistance testing revealed that 57.44% of strains were MRSA, with high resistance to Tetracycline, Ciprofloxacin, Kanamycine Erythromycin and Clindamycin. Molecular analysis showed 19.14% of strains were Pvl-positive, highlighting the presence of both MRSA and MSSA strains with Pvl genes. Conclusions. The study underscores the need for continuous surveillance and targeted infection control strategies to manage the spread of MRSA, particularly in vulnerable populations.

Source: Medicine and Pharmacy Reports

DOI: 10.15386/mpr-2783

Authors: Eftychios Vittorakis, Mihaela Laura Vica, Stanca-Lucia Pandrea, Amanda Rădulescu, Calina Oana Zervaki, Evangelos Vittorakis, Sofia Maraki, Viktoria Eirini Mavromanolaki, Michael Ewald Schürger, Vlad Sever Neculicioiu, Evangelia Papadomanolaki, Lia Monica Junie

Institutions: Iuliu Hațieganu University of Medicine and Pharmacy, Chania General Hospital ”St. George”, Institutul Regional de Gastroenterologie Prof. Dr. Octavian Fodor, University Hospital of Heraklion

Language: English

Topic: Antimicrobial Resistance in Staphylococcus

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4403774028

FWCI:

Cites: 1

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Related to: 10