Work

Association of Chronic Obstructive Pulmonary Disease Exacerbation with Type-2 Diabetes Mellitus Comorbidity: Possibility Role of IL-8

Year: 2024

Type: article

Abstract: Introduction: Type-2 Diabetes Mellitus (type-2 DM) is associated with the incidence of respiratory tract infections which is a risk factor for Chronic Obstructive Pulmonary Disease (COPD) exacerbations. Interleukin-8 (IL-8) is one of inflammatory mediators both in COPD exacerbation and pathogenesis of type 2 DM. Method: We conducted literature searched in online database PUBMED and Google Sholar, all study published since 2015 until 2024. Conclusions: IL-8 is a proinflammatory cytokine that has been shown to play a role in COPD because it triggers mucus hypersecretion and bacterial colonization which is risk factor for exacerbation of COPD and causes adipose tissue dysfunction in type 2 diabetes. Keywords: COPD exacerbation; type-2 DM; prevalence; IL-8

Source: International Journal of Research and Review

DOI: 10.52403/ijrr.20241039

Authors: Armita Dewi, Faisal Yunus, Nirwana Fitriani Walenna

Institution: Hasanuddin University

Language: English

Topic: Chronic Obstructive Pulmonary Disease (COPD) Research

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4403791864

FWCI: 0.259

Cites:

Cited by: 1

Related to: 10